Polymers have played an integral role in the advancement of drug delivery technology by providing controlled release of therapeutic agents in constant doses over long periods cyclic dosage and tunable release of both hydrophilic and hydrophobic drugs. Figure 1 drug levels in the blood with a traditional drug dosing and b controlled delivery dosing in recent years controlled drug delivery formulations and the polymers used in these systems have become much more sophisticated with the ability to do more than simply extend the effective release period for a particular drug. Polymers for drug delivery sigma aldrich offers a diverse drug delivery toolbox that includes ready to use polymer and nanoparticle chemistries for directed and controlled delivery of small and large molecule therapeutics a major challenge in drug development is ensuring that each new. Work with these polymers in controlled drug delivery systems the greatest advantage of these degradable polymers is that they are broken down into biologically acceptable molecules that are metabolized and removed from the body via normal metabolic pathways however biodegradable materials do produce degradation by. 4 polymers in novel drug delivery systems chemical engineers pharmacologists and scientists are using polymers for developing controlled drug release systems and sustained release formulations 3 novel drug delivery systems include micelles dendrimers lipo somes polymeric nanoparticles cell ghosts microcapsules and lipoproteins
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